Teixobactin: A Powerful Tool for Combating Resistant Strains
Department of Pharmaceutics, Institute of Pharmacy, Nirma University, Ahmedabad, 382481, India
Department of Pharmaceutics, Institute of Pharmacy, Nirma University, Ahmedabad, 382481, India E-mail: tejalsharm[email protected]
Resistance to antibiotics has grown out to be serious health dilemma. Despite this serious health crisis, no new antibiotics have been revealed since last 30 y. A new ray of hope in the form of teixobactin has come out of the dark which can prove to be effective in defeating resistance. This new antibiotic has an interesting mechanism of action against bacteria. The discovery of this wonderful compound has evolved as major breakthrough especially in this era of antibiotic catastrophe. This review article highlights various facets of teixobactin. Its chemistry, mode of action, in vitro and in vivo aspects have been thrown light upon in this review. Though the compound has not undergone clinical trial studies but its effect in mice models has given a hope for overpowering resistance. This article has been mainly communicated with an objective to provide information about teixobactin which has emerged as ray of hope for fighting antibiotic resistance.