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Abstract

The impact of clinical pharmacist support on patients receiving multi-drug therapy for coronary heart disease in China

Author(s): SJ Zhao1, HW Zhao1, S Du2, YH Qin1
1Department of Pharmacy, People's Hospital of Henan Province, Zhengzhou-450 003, China 2Department of Cardiovascular Medicine, People's Hospital of Henan Province, Zhengzhou-450 003, China

Correspondence Address:
Y H Qin Department of Pharmacy, People's Hospital of Henan Province, Zhengzhou-450 003 China E-mail: [email protected]


The study determined pharmacist support on patients receiving multi-drug therapy for coronary heart disease by evaluating patient self-care ability, quality of life, and drug therapy compliance. In this study, ninety patients were randomly assigned to an experimental group (n=45) and a control group (n=45). The control group received conventional clinical care. The experimental group received clinical care plus pharmacist support that included medication review, patient education, lifestyle management, discharge guidance, and telephone follow-up. Eighty-five patients completed the study. Self-care ability and quality of life were evaluated before hospital discharge. The experimental group understood their condition better than the control group (P<0.05), the differences between the groups in understanding treatment goals, drug regimens, lifestyle modifications, psychogenic disorders, and satisfaction evaluations were more pronounced (P<0.01). At six-month follow-up, the difference between the groups in drug therapy compliance was P<0.01, as was success rate by intention-to-treat (77.8% vs. 48.9%) and per-protocol (81.4% vs. 52.4%). Two adverse drug reactions occurred in the experimental group and three in the control group. Pharmacist support improved self-care ability, quality of life, drug therapy compliance, and treatment success rate in coronary heart disease patients.



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