Ultrathin multilayer capsules in drug delivery
Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University, Sagar - 470 003, India
N K Jain Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University, Sagar - 470 003 India E-mail: [email protected]
Ultra thin multilayer capsules are attractive and stable systems capable of delivering the bioactives. Ultra thin multilayer capsules consist of polyelectrolytic materials that are formed in the presence of a template. This is achieved through layer-by-layer adsorption of oppositely charged macromolecules on to colloidal particles. Upon extraction, the resulting cavities retain affinity for the bioactives. This review considers the fabrication, of ultra thin multilayer capsules, physiochemical properties and role of ultra thin multilayer capsules within a pharmaceutical remit. Ultrathin multilayer capsules have potential for creating satisfactory drug dosage forms.