All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Visible Spectorphotometric Method For The Determination Of Lomefloxacin Hydrochloride In Pharmaceutical Preparations

Author(s): A Rajasekaran, B Jaykar, S Dhanalakshmi, M Deepalakshmi, V Irine Beulah

A new spectrophotometric method is developed for the estimation of lomefloxacin hydrochloride (LFLX) in pharmaceutical dosage forms. The method is based on the reaction of LFLX with 1% W/V ferric nitrate solution in 1 % v/v nitric acid to form orange yellow coloured chromogen which exhibits absorption maximum at 445 nm. The Formation of colored chromogen is due to the interaction of quinolone derivatives with polyvalent metal ion Fe++, to form water soluble complex1. The chromogen formed is stable. Beer's law is obeyed in the concentration range of 2-10 mcg/ml.

PDF

 
 
Google scholar citation report
Citations : 66710

Indian Journal of Pharmaceutical Sciences received 66710 citations as per google scholar report