Visible spectrophotometric methods for the determination of diltiazen hydrochloride.
Dept. of Pharm. Sciences and Food and Drug Laboratories, Andhra University, Visakhapatnam
C SP Sastry Dept. of Pharm. Sciences and Food and Drug Laboratories, Andhra University, Visakhapatnam
Two simple spectrophotometric methods are described for the determination of Diltiazen Hydrochloride (DZH) based on oxidising it with a known excess of ferric chloride [Fe(III)]or N-Bromosuccinimide (NBS) and estimating the reduced, Fe (II) or unreacted NBS with 1, 10-phenanthroline (PTL) or metolsulfanilamide (SA) in methods A or B respectively.