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Abstract

Visible spectrophotometric methods for the determination of diltiazen hydrochloride.

Author(s): C SP Sastry, K Sreedhar, MN Reddy, DG Sankar
Dept. of Pharm. Sciences and Food and Drug Laboratories, Andhra University, Visakhapatnam

Correspondence Address:
C SP Sastry Dept. of Pharm. Sciences and Food and Drug Laboratories, Andhra University, Visakhapatnam

Two simple spectrophotometric methods are described for the determination of Diltiazen Hydrochloride (DZH) based on oxidising it with a known excess of ferric chloride [Fe(III)]or N-Bromosuccinimide (NBS) and estimating the reduced, Fe (II) or unreacted NBS with 1, 10-phenanthroline (PTL) or metolsulfanilamide (SA) in methods A or B respectively.