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| Year : 1988 | Volume
: 50
| Issue : 2 | Page : 114-117 |
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Determination of pyrimethamine in drug preparations by fluorimetry.
P Parimoo
Dept. of Pharmacy, B.I.T.S., Pilani,
Correspondence Address:
P Parimoo
Dept. of Pharmacy, B.I.T.S., Pilani
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A simple and sensitive fluorimetric procedure is described for the analysis of pyrimethamine in dosage forms depending on its strong fluorescence in 1 normal sulphuric acid (lamda excitation = 321 nm, (lamda emission = 425 nm) with a detection limit of 1 mug/ml. The addition of molecules of sulfodoxine cause a quenching in the region of excitation and emission of the former compound. |
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