Indian Journal of Pharmaceutical Sciences
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Scientific Publication of the Indian Pharmaceutical Association
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Year : 1988  |  Volume : 50  |  Issue : 2  |  Page : 138-140

Spectrophotometric determination of sulphacetamide sodium with o-chloranil in dosage forms.


Quality Control Laboratories, I.D.P.L., Hyderabad-500 037,

Correspondence Address:
G R Rao
Quality Control Laboratories, I.D.P.L., Hyderabad-500 037

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A spectrophotometric method for the estimation of sulphacetamide based on its reaction with o-Chloranil at pH 9.0 yielding a purple coloured chromogen with absorption maximum at 525 nm is reported. Beer's law is obeyed over the concentration range 10 to 70 mug/ml of sulphacetamide sodium. The proposed method is applicable to pharmaceutical preparations.


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