Indian Journal of Pharmaceutical Sciences
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Scientific Publication of the Indian Pharmaceutical Association
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Year : 1999  |  Volume : 61  |  Issue : 6  |  Page : 389-391

Development Of A Protein-Based Model Microparticle Drug Delivery System


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A Bhattacharya


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A new generation model drug mianserine is microencapsulated in protein. Lipid soluble pure mianserine was emulsified under optimized conditions in aqueous protein solution using isopropanol as co-emulsifier. Resultant clear microemulsion can readily be used through a micronized spray in denaturation solvent environment to produce fairly uniform protein coated microcapsules. Particle size distribution, particle character was analysed in SEM and in vitro drug release studied.


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