Indian Journal of Pharmaceutical Sciences
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Scientific Publication of the Indian Pharmaceutical Association
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Year : 1999  |  Volume : 61  |  Issue : 6  |  Page : 394-395

A New Spectrophotometric Method For The Determination Of Nitrendipine


Correspondence Address:
K Girish Kumar

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A simple and sensitive spectrophotometric method for the determination of nitrendipine is described. The method is based on the reaction of reduced nitrendipine with 3-methyl-2-benzo-thiazolinone hydrazone hydrochloride (MBTH) in the presence of ferric chloride to form a green colored chromogen with an absorption maximum of 670 nm. The color obeyed Beer's law in the concentration range of 2-10 mg/ml.

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