Indian Journal of Pharmaceutical Sciences
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Scientific Publication of the Indian Pharmaceutical Association
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Year : 2005  |  Volume : 67  |  Issue : 6  |  Page : 710-715

Isolation And hypotensive Activity Of New Phytoconstituents From Chloroform Extract Of Hibiscus Rosasinensis Linn Flowers


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A. A Siddiqui


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Three extracts of Hibiscus rosasinensis Linn have been prepared and hypotensive activity was evaluated. Hydroalcoholic extract was found to exhibit prominent activity when compared to the reference standard minoxidil followed by chloroform extract. In an attempt to isolate the active constituents responsible for this activity, five new phytoconstituents were isolated and their structures were elucidated from spectral evidence (IR, NMR and Mass spectra). Hypotensive activity of these compounds was also studied.


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