| SHORT COMMUNICATION |
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| Year : 2007 | Volume
: 69
| Issue : 2 | Page : 303-304 |
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Extractive spectrophotometric method for determination of carvedilol in tablets
JK Verma, HA Syed
Department of Chemistry, K. J. Somaiya College of Science and Commerce, Vidyavihar, Mumbai - 400 077, India
Correspondence Address:
J K Verma
Department of Chemistry, K. J. Somaiya College of Science and Commerce, Vidyavihar, Mumbai - 400 077
India
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DOI: 10.4103/0250-474X.33166
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A sensitive and rapid extractive spectrophotometer method has been developed for the assay of carvedilol in pharmaceutical formulations. The method is based on the formation of a chloroform soluble ion-pair complex between carvedilol and bromocresol green in an acidic medium. The complex shows absorption maximum at 415 nm and the system obeys Beer's law in the concentration range of 5-25 µg/ml. The results obtained by the proposed method were validated statistically and by recovery studies. |
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