Year : 2004 | Volume
: 66 | Issue : 1 | Page : 82--86
Synthesis And Antimicrobial Activity Of Some Novel 6-Bromo-2-Methyl/phenyl-3-(Sulphonamido) quinazolin-4(3H)- Ones
P Selvam, K Vanitha, M Chandramohan, E De Clercq
,
Correspondence Address:
P Selvam
A series of novel 2-substituted-3-(sulphonamido) quinazolin-4 (3H)-ones have been synthesized by condensing the primary amino group of sulphamoxole and sulphadimidine with 2-substituted benzoxazin-2-one. The compounds synthesized were screened for antibacterial activity
(Escherichia coli and Staphylococcus aureus) antiviral activity (Herpes simplex virus type 1 and 2 in E6SM cells, HIV-1 and 2 in MT-4 cells), all the test compounds exhibited comparable antibacterial activity with that of standards sulphamoxole and sulphadimidine.
How to cite this article:
Selvam P, Vanitha K, Chandramohan M, De Clercq E. Synthesis And Antimicrobial Activity Of Some Novel 6-Bromo-2-Methyl/phenyl-3-(Sulphonamido) quinazolin-4(3H)- Ones.Indian J Pharm Sci 2004;66:82-86
|
How to cite this URL:
Selvam P, Vanitha K, Chandramohan M, De Clercq E. Synthesis And Antimicrobial Activity Of Some Novel 6-Bromo-2-Methyl/phenyl-3-(Sulphonamido) quinazolin-4(3H)- Ones. Indian J Pharm Sci [serial online] 2004 [cited 2013 Jun 20 ];66:82-86
Available from: http://www.ijpsonline.com/article.asp?issn=0250-474X;year=2004;volume=66;issue=1;spage=82;epage=86;aulast=Selvam;type=0 |
|
|
|
