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pharmaceutical sciences

 
Review Article p. 1

Traditional Uses, Phytochemistry and Pharmacological Activities of Woodfordia fruticosa (L) Kurz: A Comprehensive Review

Simran Giri, G. Dey, R. Sahu, Paramita Paul, G. Nandi and T. K. Dua*

Woodfordia fruticosa (L.) kurz belongs to the family 'Lythraceae' has been utilized in traditional medicine for treating common ailments since ancient periods. It is conventionally employed ..

Review Article p. 13

Nanocochleates and Drug-Phospholipid Complex: Novel Approaches for Phospholipid Based Oral Delivery of Anti-Cancer Agents

K. Mulrajani, N. Rajnani and N. Kurup*

Phospholipids have managed to overcome several challenges, which hampered the therapeutic potential of conventional drug delivery systems. As formulation excipients, phospholipids have becom..

Research Paper p. 23

Biosynthesis, Characterization and Evaluation of Antimicrobial, Antioxidant and Antiproliferiative Activities of Biogenic Silver Nanoparticles Using Streptomyces KBR3

J. Samuel, M. M. Selvam, K. Manigundan, Baskaran Abirami, S. Thangavel and R. K. Manikkam*

Facile synthesis of silver nanoparticles was attempted using soil derived Streptomyces sp. KBR3 and its antimicrobial, antioxidant and antiproliferiative properties were evaluated in vitro. ..

Research Paper p. 31

Effects of Jatrorrhizine on Proliferation, Apoptosis and Invasion of Breast Cancer Cells by Regulating Wnt/Beta-Catenin Signaling Pathway

Shuai Zhao and Yu Wang*

To explore the effects of jatrorrhizine on proliferation, apoptosis, migration and invasion of breast cancer cells via the regulation of Wnt/β-catenin signaling pathway. Breast cance..

Research Paper p. 37

Relieving Effect of Naringenin on Constipation in Mice and Its Effect on Intestinal Flora in Mice

Xiaojuan Zhu, X. Liu and Zheng Liu*

To look into how naringenin affects mice's intestinal flora and alleviation from constipation. The four groups control, model, positive drug and naringenin, each with ten mice were formed..

Research Paper p. 44

Molecular Docking study of Severe Acute Respiratory Syndrome Coronavirus 2 Spike Glycoprotein with Celastroid Triterpenoid Inhibitors

Bhaskar Bagchi* and Tamal Goswami

Severe acute respiratory syndrome coronavirus 2 poses a huge threat to humans. The β genus Severe acute respiratory syndrome coronavirus 2 has four structural proteins: Spike, envelo..

Research Paper p. 53

Effects of Water Miscible Organic Co-solvents on Enzyme Kinetic Parameters of Drug Metabolizing Enzymes in Rat Liver Microsomes

S. H. Kamble, Deepali Desle and K. R. Iyer*

We have investigated the effects of methanol, acetonitrile, dimethyl sulphoxide or dioxane on enzyme kinetic parameters (Km and Vmax) of p-nitrophenol hydroxylation, phenacetin deethylati..

Research Paper p. 64

Comparative Analysis of Natural Bioactive Metabolites of the Indigenous Host Plants of Muga Silkworm for Antioxidant and Antibacterial Properties against Swine Diseases

Manasee Choudhury, Shamima Parbin, Seema Pegu, S. Banik and P. J. Das*

The present study explores the natural bioactive metabolites, antioxidant and antibacterial activities present in the host plants of Antheraea assamensis (muga silkworm) viz. Machilus bom..