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Abstract

Antioxidant And Antiinflammatory Properties Of Citrus Sinensis Peel Extract

Author(s): S Ramachandran, J Anbu, M Saravanan, S Kishore Gnanasam, S. K Sridhar

In the present study, the antioxidant and antiinflammatory properties of methanolic extract of Citrus sinensis peel was investigated. Qualitative tests confirmed the presence of flavanoids and free phenolic compounds in the extract. The antioxidant property of the extract was tested qualitatively by thin layer chromatography using β-carotene-linoieate oxidation-The anti-inflammatory activity of the extract was performed on carrageenan- induced acute pedal paw edema model and Freund's complete adjuvant-induced chronic inflammatory model. In both acute and chronic anti- Inflammatory models, the extract exhibited significant antiinflammatory activity at two doses of 150 and 300 mg/kg.