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Review Article p. 385

Glycerosomes: Advanced Liposomal Drug Delivery System

Priya Gupta*, Rupa Mazumder and Swarupanjali Padhi

Although liposomes have proved to be versatile in the field of drug delivery, there are still some issues that need to be addressed mainly problems related to entrapment, penetration, fluidi..

Research Paper p. 398

Withania somnifera Ameliorates Aluminium Chloride-induced Testicular Toxicity and Impaired Fertility in Mus musculus

P. Kumar and Poonam Singh*

The present study was planned to evaluate the effectiveness of Withania somnifera against aluminium chloride-induced testicular toxicity and impaired fertility. Swiss mice were divided into ..

Research Paper p. 409

MicroRNA Expression Profiles in C6 Glioblastoma Cell Line Treated with Antipsychotics

T. S. Wang, Y. C. Chen, F. M. Tsai, , Y. Y. Chang , Y. H. Chen , C. Y. Kuo and M. L. Chen,*

In the present investigation antipsychotic drug-induced miRNA modulations in glial cells were analyzed through miRNA expression in antipsychotic drugs-treated C6 cells using a miRNA microarr..

Research Paper p. 420

Beta-Amyrin Modulates P38 MAPK and Jnk Pathway to Inhibit Cell Proliferation and Induce ROS-mediated Apoptosis in HeLa Cells

J. Anburaj, Tamilselvi*, Sanni Swapna, Kamati Amuthavalli

It is aimed to investigate the effect of ?-amyrin on p38 mitogen-activated protein kinase and Jun N-terminal kinase pathways and apoptosis in HeLa cells. HeLa treated cells were divided into..

Research Paper p. 429

A Novel LC-MS/MS Method Development and Validation for Ultra-trace Level Determination of Three Genotoxic Efavirenz Impurities

Annapoorna Vadlamani* and K. Ravindhranath

A novel, simple, sensitive, specific and rapid reverse-phase liquid chromatography-electrospray ionization-mass spectrometry method was established and validated for the ultra-trace analysis..

Research Paper p. 435

Development and Characterization of Colon-targeting 5-Fluorouracil Multiparticulate Beads

M. K. Sarangi*, M. E. Bhanoji Rao,, Versha Parcha and A. Upadhyay

This investigation is related to the development and optimization of multiparticulate beads of fenugreek seed mucilage-sodium alginate containing 5-flurouracil through ionotropic gelation te..

Research Paper p. 449

HPTLC Analysis, Antioxidant and Antidiabetic activities of Ethanol Extract of Moss Fissidens grandiflora

Ho Viet Hieu, V. B. Tatipamula,, K. N. Killari,*, Sree Teja Koneru, Nallapaty Srilakshmi and S. K. Ranajith

The phytochemical composition, antioxidant and antidiabetic profile of ethanol extract of Fissidens grandiflora was investigated for the first time. The phytochemical analysis of Fissidens g..

Research Paper p. 456

Mongolian Chelidonium majus Suppresses Metastatic Potential of Hepatocellular Carcinoma Cells through TIMP Up-regulation and MMP Down-regulation

H. Hong, D. Baatar, O. Sukhbaatar, S. H. Yang and S. G. Hwang*

In this study, the antimetastatic effect of Chelidonium majus ethanol extract on hepatocellular carcinoma in vitro was investigated. The viability of SK-Hep1 and normal liver cells was deter..