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Abstract

Computer Simulation Of In Vitro Drug Release Data And Its Kinetic Interpretation

Author(s): P. R. P Verma, T. E. G. K Murthy, V Ramesh

In view of the limited information available on computer simulation of in vitro drug release data, a software is developed in a structured language 'C'. Upon feeding the values of absorbances and time data, the values of percent cumulative drug release, percent drug unreleased, log percent drug unreleased and finally the coefficient of correlation values for zero order, Higuchi model and first order are displayed in a tabular form which helps in predicting the actual release kinetics. The Unix 'C' is simple, useful and intelligible.