Determination Of Acetaminophen In Presence Of Codeine In Pharmaceutical Formulations By Derivative Spectrophotometry
First derivative U.V. spectrophotometry has been used for the assay of acetaminophen in presence of codeine. Acetaminophen has been assayed by measuring the first derivative absorbances at 263.4 nm. The concentration of acetaminophen has been calculated without interference of codeine. The procedure is simple and rapid, and provides accurate and precise results.