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Abstract

Extractive spectrophotometric determination of some anthelmintics using fast green FCF or orange-II.

Author(s): C SP Sastry, M Aruna, MN Reddy, DG Sankar
Foods, Drugs and Water Laboratories, School of Chemistry, Andhra University, Waltair 530 003,

Correspondence Address:
C SP Sastry Foods, Drugs and Water Laboratories, School of Chemistry, Andhra University, Waltair 530 003

Two senstive methods for the determination of diethylcarbamazine citrate, bephenium hydroxynapthoate, tetramisole hydrochloride and levamisole hydrochloride based on the formation of coloured complexes of the drug with reagents such as fast green FCF at pH 5.0 or orange-II in presence of O.IN HCI are described in bulk samples and pharmaceutical preparations. The ion-pair complexes foemed are quantitatively extracted into chloroform under the experimental conditions.