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Abstract

Hepatoprotective Activity Of Rhizomes Of Cyperus Rotundus Linn Against Carbon Tetrachloride-Induced Hepatotoxicity

Author(s): S. V Suresh Kumar, S. H Mishra

Ethyl acetate extract and two crude fractions, solvent ether and ethyl acetate, of the rhizomes of Cyperus rotundus (Cyperaceae) were evaluated for hepatoprotective activity in rats by inducing liver damage by carbon tetrachloride. The ethyl acetate extract at an oral dose of 100 mg/kg exhibited a significant protective effect by lowering serum levels of glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, alkaline phosphatase and total bilirubin. These biochemical observations were supplemented by histopathological examination of liver sections. Silymarin was used as positive control.