All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Microwave assisted synthesis and pharmacological evaluation of some potent naphtho and benzofuro thiazolyl, oxazolyl, thio and oxadiazalyl derivatives

Author(s): DB Aruna Kumar1, GK Prakash2, BP Nandeshwarappa3, BM Kiran1, BS Sherigara3, KM Mahadevan1
1 Department of PG Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, Jnana Sahyadri, Shankaraghatta-577 451, India 2 Institute of Wood Science and Technology, Malleshwaram, Bangalore-560 003, India 3 Department of PG Studies and Research in Industrial Chemistry, School of Chemical Sciences, Kuvempu University, Jnana Sahyadri, Shankaraghatta-577 451, India

Correspondence Address:
K M Mahadevan Department of PG Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, Jnana Sahyadri, Shankaraghatta-577 451 India E-mail: [email protected]


The substituted 2-acetyl benzofurans on bromination gave substituted 2-(2-bromoacetyl) benzofurans 2a-f. These on reaction with thiourea, urea, thiosemicarbazide and semicarbazide in presence of sodium acetate under microwave irradiation resulted 3a-f, 4a-f, 5a-f and 6a-f respectively. The structures of newly synthesised compounds have been established by elemental analysis, spectral data and screened for antimicrobial, anthelmintic, antiinflammatory and analgesic activities.



Share this