New Microwave Methods For Rapid Quantitative And Quantitative Analysis And Loss On Drying
Reactions carried out under microwave irradiation are found to be faster and the technique is being used in laboratories for a variety of purposes. In order to introduce microwave technique for pharmaceutical chemistry practical, its use in quantitative and qualitative analysis and loss on drying is discussed. Quantitative estimation of amide, ester, and carbonyl compounds was successfully carried out. The percent purity obtained for all the samples was higher than those obtained through conventional methods and the time consumed was also found to be less by the microwave technique. Preparation of nitrate, oxime and hydrazone derivatives of organic molecules was successfully completed in a short duration. Determination of loss on drying was also achieved in a shorter duration. The procedures developed can be used for routine analysis in Pharmaceutical Chemistry laboratories.