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Abstract

Quinazolinones As Potential Anti-Inflammatory Agents

Author(s): Ritu Tyagi, Bhawna Goel, V. K Srivastava, A Kumar

2-Methyl-3-arylidenamino-4 (3H)-quinazolinones (la-le) on cyclocondensation with thiolactic acid and diazomethane are converted into thiazolidinyl quinazolinones (IIa-IIe) and triazolidinyl quinazolinones (IIIa-IIIe) respectively. Their structures have been delineated by IR, 1HNMR and mass spectroscopy. The compounds were evaluated for anti-inflammatory activity.