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Abstract

Simultaneous Spectrophotometric Estimation Of Triprolidine Hydrochloride And Pseudoephedrine Hydrochloride In Pharmaceutical Dosage Form

Author(s): R Moharana, N Kawathekar, S. C Chaturvedi

A method for simultaneous spectrophotometric estimation of triprolidine hydrochloride and pseudoephedrine hydrochloride in combined tablet dosage form was established, based on the proportional isoabsorption point (PIP) method. The proposed method uses the absorbance at the PIP at 290 nm and at the absorbance maxima of the combined spectrum at 266nm using 0.1 N hydrochloric acid as the solvent. The results of analysis of tablet formulation by the proposed method are in agreement with the results obtained by a reported method. The recovery studies carried out gave results between 99.6 to 100%.