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Abstract

Spectrophotometric Determination Of Carvedilol From Bulk And Formulations

Author(s): P. S Jain, G. S Talele, S. G Talele, S. J Surana

A new, simple, sensitive spectrophotometric method in ultraviolet region has been developed for the determination of carvedilol in bulk and in pharmaceutical formulations. Carvedilol exhibited maximum absorbance at 285 nm with apparent molar absorptivity of 15.4x103 I/mol.cm in methanol. Beer's law was found to be obeyed in the concentration range of 4-36 μg/ml. Results of theanalysis were validated statistically and by recovery studies.