All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Spectrophotometric determination of cefetamet pivoxil hydrochloride and pitavastatin calcium in tablet dosage form

Author(s): NH Vadia, Vandana Patel, HN Bhalara
Pharmaceutical Quality Assurance Laboratory, The Maharaja Sayajirao University of Baroda, India

Correspondence Address:
Vandana Patel Pharmaceutical Quality Assurance Laboratory, The Maharaja Sayajirao University of Baroda, India India E-mail: [email protected]


Two simple, rapid, specific and accurate analytical methods for the estimation of cefetamet pivoxil hydrochloride and pitavastatin calcium in bulk drug and in their tablet formulations are described. These methods are based on difference spectrophotometry, wherein the measurement is done at maximum 221 nm and minimum 275 nm for cefetamet whereas at maximum 240 nm and minimum 259 nm for pitavastatin. The Beer's law was obeyed in the concentration range of 1-35 µg/ml and 1-25 µg/ml and the molar absorptivities were 1.3×10 4 lit mol -1 cm -1 and 2.4×10 4 lit mol -1 cm -1 for cefetamet pivoxil hydrochloride and pitavastatin calcium, respectively. The proposed methods were validated and successfully applied to the estimation of drugs in tablet formulations.



Share this