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Abstract

Spectrophotometric determination of diclofenac sodium in pharmaceutical dosage forms.

Author(s): AK Shakya, GK Joshi, P Mishra
Department of Pharmaceutical Sciences, Doctor Harisingh Gour, Vishwavidyalaya, Sagar-470 003,

Correspondence Address:
A K Shakya Department of Pharmaceutical Sciences, Doctor Harisingh Gour, Vishwavidyalaya, Sagar-470 003

A simple colorimetric method is described for the determination of diclofenac sodium in pharmaceutical formulation based on the reaction of the drug in acidic media with sodium cobalti nitrite to form a light yellow colored complex ( lambda max 368 nm ) which obeys Beer's Law in 25 - 125 mug/ml concentration range.