Spectrophotometric determination of sulphacetamide sodium with o-chloranil in dosage forms.
Quality Control Laboratories, I.D.P.L., Hyderabad-500 037,
G R Rao Quality Control Laboratories, I.D.P.L., Hyderabad-500 037
A spectrophotometric method for the estimation of sulphacetamide based on its reaction with o-Chloranil at pH 9.0 yielding a purple coloured chromogen with absorption maximum at 525 nm is reported. Beer's law is obeyed over the concentration range 10 to 70 mug/ml of sulphacetamide sodium. The proposed method is applicable to pharmaceutical preparations.