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Abstract

Studies on the antimicrobial potential of Mahonia leschenaultii Takeda root and root bark

Author(s): B Duraiswamy, Sagar Kumar Mishra, V Subhashini, SA Dhanraj, B Suresh
Department of Pharmacognosy, J. S. S. College of Pharmacy, Rocklands, (P.B. No. 20), Ootacamund-643 001, India

Correspondence Address:
B Duraiswamy Department of Pharmacognosy, J. S. S. College of Pharmacy, Rocklands, (P.B. No. 20), Ootacamund-643 001 India E-mail: [email protected]


The methanol extracts of Mahonia leschenaultii takeda (Berberidaceae) root and root bark were tested for antibacterial potential against Escherichia coli (NCIM 2068), Pseudomonas aeruginosa (NCIM 2053), Staphylococcus aureus (NCIM 2492), and Staphylococcus epidermitis (NCIM 2493) on nutrient agar medium and nutrient broth using ampicillin trihydrate as standard drug. For antifungal study, stains used were Trichophytons lignorum (NCIM 1195) and Candida crusei (NCIM 3129) on Sabourauds dextrose agar (SDA) and Sabourauds dextrose broth (SDB) by cup plate method using amphotericin B as standard drug. The results showed that all extracts exhibited significant activity against all the selected strains of bacteria and relatively more against Staphylococcus epidermitis . The antifugal activity was less significant when compared with antibacterial activity.



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