Study of abietic acid-sorbitol derivatives as microencapsulating materials.
Dept. of Pharmaceutical Sciences, Nagpur University Campus, Nagpur-440 010
P K Puranik Dept. of Pharmaceutical Sciences, Nagpur University Campus, Nagpur-440 010
Abietic acid was isolated from rosin N Grade. Abietic acid-sorbitol derivatives were prepared and evaluated for their physicochemical properties and as material for microencapsulation by pan coating technique, using salicylic acid as a model drug. The coated microcapsules were evaluated for moisture absorption, flow properties, friability and release characteristics. The result showed that the materials having lower acid values possedd moisture protection properties and also prolong the release of the drug.