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Abstract

Synthesis & antibacterial activity of some new flurinated pyrido [2,3-d] pyrimidine derivatives.

Author(s): Shaihla, SS Verma, S Malik, RL Mital, L Prakash
Dept. of Chemistry, University of Rajasthan, Jaipur-302 004,

Correspondence Address:
Shaihla Dept. of Chemistry, University of Rajasthan, Jaipur-302 004

Flurinated 4-imino-3,5,7-trisubstituted pyrido [2,3-d] pyrimidine-2 (1H)-thiones were prepared by 2-amino-3 cyano-4, 6-disubstituted-pyridines and appropriate arylisothiocyanates, and characterised. The antibacterial activity of all the pyrido[2,3-d]-pyrimidines has been evaluated and found active against S.aureas.