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Abstract

Synthesis And Biological Activities Of 1-[(3,4-Dihydro-3-Oxo-2h-1,4-Benzoxazin-2-Yl) Acetyl]-3,4-Disubstitued Pyrazoles And 3-Methyl-Pyrazolinones

Author(s): Y Jayamma, V Malla Reddy

Some new 1-[(3,4-dihydro-3-oxo-2H-1, 4-benzoxazin-2yl) acetyl]-3, 4-disubstituted pyrazoles (II) and 1-[(3,4-dihydro –3-oxo-2H-1, 4- benzoxazin – 2yl)-3-methyl pyrazolin-5-ones (III) have been synthesized and tested for their (II) antimicrobial activity. Some of the exhibit a significant antimicrobial activity, compound lla has been found to possess antihistaminic activity.