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Abstract

Synthesis And Biological Evaluation Of 4-(Substituted Aryl)-1-(N-Indolyl Acetamidyl)-3-Chloro-2-Azetidinones

Author(s): P. V. R Chowdary, S. G Jawarkar, K Shashikala Rani, Girija Rao, V Prasad

Various 4-(substituted aryl)-1-(N-indolyl acetamidyl)-3-chloro-2-azetidinones were prepared by condensing N-(arylidine hydrazidomethyl)-indoles with chloroacetyl chloride. Their structures were established by chemical tests, IR and 1HNMR spectral data. These synthesized compounds were tested for their antibacterial, antifungal, antitubercular and antiinflammatory activities.