All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Synthesis of 3,6-diaryl-2H, 3H, 4H, 5H, 6H-[1,3]-Oxazine-2- Thiones As Potential Anticonvulsants

Author(s): C Singh, H. K Parwana, G Singh

It is reported that (-NH-C) and (-C-NH-C) groups are associated with the analgesic and muscle relaxation properties. Therefore, synthesis of eight cyclic thiocarbamates, 3,6-dairly pentahydro- [1,3]-oxazine-2-thiones as potential anticonvulsant drugs have been attempted through cyclisation with thiophosgene of 1-arylamino-3-hydroxy-3-arylpropanes obtained earlier by hydride reduction of 1-arylamino-3-oxo-3-arylpropanes.