All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Synthesis, UV/Vis and Fluorescence studies of Naphthoquinone Pyridyl Tetrazole-based Chemical Probe

Author(s): K. Balakrishna, D. Vijaya Lakshmi, S. Mustafa*, K. S. Reddy and T. K. Ghorpade1
Department of Chemistry, GITAM University, Hyderabad campus, Rudraram, Hyderabad-502 329, 1Polymer Science and Technology Centre, Naval Materials Research Laboratory, Ambernath, Maharastra-421 506, India

Correspondence Address:
Department of Chemistry, GITAM University, Hyderabad campus, Rudraram, Hyderabad-502 329, India, E-mail: [email protected]


2-(dimethylamino)-3-(5-(pyridin-2-yl)-1H-tetrazol-1-yl)naphthalene-1,4-dione (2) has been synthesized. The UV/Vis studies of 2-(dimethylamino)-3-(5-(pyridin-2-yl)-1H-tetrazol-1-yl)naphthalene-1,4-dione (2) with different metal ions were performed in aqueous dimethylformamide and were correlated with fluorescence studies of the same. The compound showed higher selectivity and sensitivity for Zn2+ ions. Thus this compound could be utilized as a turn-on probe for fluorescent imaging of Zn2+ ions in living cells.



Share this