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Abstract

Three Simple Spectrophotometric Methods For The Assay Of Ketotifen In Pharmaceutical Formulations

Author(s): C. S. P Sastry, P. Y Naidu, S. S. N Murty

Three simple and sensitive spectrophotometric methods for the determination of ketotifen based on the formation of a charge-transfer complex between ketotifen and chloranilic acid (method A, lmax : 550nm), by the inner molecular complex with sodium nitroprusside (method B, lmax : 770 nm) or oxidation with excess potassium permanganate and the determination of unconsumed permanganate using Fast Green FCF (method C, lmax : 625 nm) have been developed.