UV Spectroscopic And Colorimetric Methods For The Estimation Of Cefdinir In Capsule Dosage Forms
Two simple and sensitive spectroscopic methods in ultraviolet and visible region were developed for the estimation of cefdinir in pharmaceutical dosage forms. In method A cefdinir showed absorption maximum at 287 nm in 0.1 M phosphate buffer (pH 7.0), whereas in method B, it reacted with Folin-Ciocalteu reagent under alkaline conditions forming a blue coloured chromogen having absorption maximum at 720 nm. These methods obey Beer's law in the concentration range of 3 to 17 Î¼g/ml and 4 to 20 Î¼g/ml, respectively. The methods are statistically evaluated for accuracy and precision.