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A Colorimetric Assay Method For Nabumetone

Author(s): Y Srinivasa Rao, K.P.R Chowdary, J.V.L.N Seshagiri Rao

A simple spectrophotometric method has been developed for the estimation of nabumetone in pure and pharmaceutical dosage forms. In this method, the drug is made to react with ferric chlorideand 1,10-phenanthroline when a red complex is formed. The chromogen can be estimated at 517 nm against a reagent blank. The method obeys Beer's law in the concentration range of 1-5μg/ml of the drug.


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