Abstract

This research aims to discuss the clinical efficacy of Xuebijing joint Maxing Shigan decoction treatment in severe pneumonia patients, in the meantime to discuss the effects of drugs combination on inflammation indicators, arterial blood gases and clinical safety. We chose 120 patients with severe pneumonia in our hospital as the study cohort. Divided them into control group (n=60) and observation group (n=60). Control group received antibiotics. observation group received antibiotics as well but combined with Xuebijing and Maxing Shigan decoction. Compared both groups in clinical effective rate, inflammation index, arterial blood gas and the incidence of drug related complications after treatment. After treatment, observation group's inflammation indexes (C-reactive protein, procalcitonin), arterial blood gas changes (partial pressure of oxygen, partial pressure of carbon dioxide) and traditional Chinese medicine syndrome scores were significantly reduced (p<0.05). The clinical efficacy of observation group was higher than the other (p<0.05), it possessed no remarkable difference in both groups complications rate (p>0.05) and it was of no statistical difference. Xuebijing combined with Maxing Shigan decoction can effectively treat patients with severe pneumonia. The clinical symptoms are significantly improved, and inflammation indicators and arterial blood gas conditions can be improved without increasing the adverse incidence and complications of drugs. The combined use is worthwhile for patients with severe pneumonia.