All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Antifungal activity of Millingtonia hortensis

Author(s): M Sharma1, S Puri2, PD Sharma1
1 University Institute of Pharmaceutical Sciences, Punjab University, Chandigarh - 160 014, India 2 Department of Biotechnology, Punjabi University, Patiala - 140 071, India

Correspondence Address:
P D Sharma University Institute of Pharmaceutical Sciences, Punjab University, Chandigarh - 160 014 India E-mail: pritamdevsharma@hotmail.com


Antifungal activities of different extracts of Millingtonia hortensis were investigated against various fungal pathogens. Methanol extract was found to have stronger activity than fluconazole against yeast like fungi: 4 fold against Candida krusei with 4 µg/ml minimal inhibitory concentration and 2 fold (MIC- 2 µg/ml) against Sacharomyces cerevisiae , though it showed the same activity as fluconazole against Candida glabrata . Aqueous extract also exhibited 4 fold stronger activity against Candida krusei (MIC- 4 µg/ml) and 4 fold (MIC; 2 µg/ml) against Sacharomyces cerevisiae . Chloroform and ethyl acetate extract showed lower activities against all fungal pathogens except for Candida krusei, compared with the standard. Against the filamentous fungus, Trichosporon cutaneum , all extracts showed less activity than the standard.

Full-Text | PDF

 
 
Google scholar citation report
Citations : 69022

Indian Journal of Pharmaceutical Sciences received 69022 citations as per google scholar report