All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


AntiHIV, Antibacterial And Antifungal Activities Of Some 2,3-Disubstituted Quinazolin-4(3H)-Ones

Author(s): V Alagarsamy, R Revathi, S Meena, K. V Ramaseshu, S Rajasekaran, E De Clerco

The title compounds 2-mercapto-3-(substitutedmethylamino) quinazolin-4(3H)-ones were synthesized by condensing the active hydrogen atom of 3-amino group of 3-amino-2-mercapto quinazolin- 4(3H)-one with formaldehyde and the desired amines. Investigation of antimicrobial activity of the compounds was performed by agar dilution method against 6 pathogenic bacteria, 3 pathogenic fungi and antiHlV activity against replication of HIV-1 (IIIB) and HIV-2 (ROD) in MT-4 cells. The compounds exhibited significant antibacterial and antifungal activities.


Google scholar citation report
Citations : 53647

Indian Journal of Pharmaceutical Sciences received 53647 citations as per google scholar report