Abstract

In the present study, the bark of Machilus macrantha Nees. (Lauraceae) was investigated for antiinflammatory activity in carrageenan-induced rat paw oedema. The alcoholic and aqueous extract showed dose-dependent inhibition of rat paw oedema, at per oral doses of 100 and 200 mg/kg, when compared to control group. The activity was compared with that of the standard drug, diclofenac sodium (15 mg/kg, p. o.)