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Antiinflammatory activity of Piper longum fruit oil

Author(s): A Kumar1, S Panghal1, SS Mallapur1, M Kumar2, Veerma Ram2, BK Singh3
1 M. M. C. P., M. M. University, Mullana, Ambala-133 203, India 2 Department of Pharmaceutical Sciences, S. B. S. P. G. I., Dehradun-248 161, India 3 Department of Pharmacy, Kumaon University, Nainital- 263136, India

Correspondence Address:
A Kumar M. M. C. P., M. M. University, Mullana, Ambala-133 203 India [email protected]

In the present study, antiinflammatory activity of the Piper longum dried fruit's oil was studied in rats using the carrageenan-induced right hind paw edema method. The activity was compared with that of standard drug ibuprofen. The dried fruit's oil inhibited carrageenan-induced rat paw edema. The results indicated that the dried fruit's oil produced significant (p< 0.001) antiinflammatory activity when compared with the standard and untreated control.

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