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Antimicrobial Activity Of Extracts Of Acalypha Indica Linn

Author(s): V Gopalakrishnan, K N V Rao, V Loganathan, S Shanmuganathan, V K Bollu, T Bhavana Sarma

Dilution method was employed to determine the effect of petroleum ether extract (40-60O) chloroform and methanolic extract of dried leaves of Acalypha indica Linn (Euphorbiaceae) against fungi (Candida albicans) and bacteria (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhosa, Bacillus substilis, Klebsiella pneumoniae). Except the petroleum ether extract, all the extracts exhibited a prominent antimicrobial activity. The methanolic extract was further fractionated into acetone soluble and insoluble parts. Both the parts exhibited prominent antimicrobial activity. The acetone insoluble part exhibited MIC of 0.0040 mg/ml against Staphylococcus aureus and both acetone soluble and insoluble parts exhibited MIC of 0.05 mg/ml against Salmonella typhosa.