Abstract

Author(s): M Saeedi¹, K Morteza-Semnani², MR Mahdavi³, F Rahimi^2
1Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, POBox 48175-861, Sari, Iran ²Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, POBox 48175-86, Sari, Iran ³Department of Laboratory Sciences, Faculty of Paraclinical Sciences, Mazandaran University of Medical Sciences, POBox 48175-861, Sari, Iran

Correspondence Address:
K Morteza-Semnani Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, POBox 48175-86, Sari Iran E-mail: ksemnani@yahoo.com

The antimicrobial activity of the methanol extracts of the dried flowering aerial parts of Stachys byzantina , S. inflata , S. lavandulifolia and S. laxa (Labiatae) were studied using the disc diffusion method and determination of minimum inhibitory concentration (MIC) values against Staphylococcus aureus , Streptococcus sanguis , Escherichia coli , Pseudomonas aeroginosa , Klebsiella pneumoniae , Aspergilus niger and Candida albicans . The extracts of plants exhibited concentration-dependent antibacterial activity against the bacteria tested. The extracts were more active against Gram-positive microorganisms. The extracts, however, did not show any antifungal activity.

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