All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Association Study between Serum Triglyceride Level and Glucose and Lipid Metabolism in Patients with Polycystic Ovary Syndrome

Author(s): JING TANG, SHAO JUN. WU* AND HUA QIAN
Department of Obstetrics and Gynecology, Taizhou People’s Hospital, No. 399 South Hailing Road,Taizhou, Jiangsu 225300, China

Correspondence Address:
SHAO JUN. WU, Department of Obstetrics and Gynecology, Taizhou People’s Hospital, No. 399 South Hailing Road,Taizhou, Jiangsu 225300, China; E-mail: [email protected]


To investigate the serum triglyceride levels and their correlation with glycolipid metabolism in patients with polycystic ovary syndrome. 108 patients who were diagnosed with polycystic ovary syndrome for the first time at the Department of Obstetrics and Gynecology of our hospital from May 2018 to June 2019 were collected. They were divided into an obesity group (n=64) and a non-obesity group (n=36) according to body mass index and a control group of 36 healthy medical examiners with body mass index similar to those of the patients during the same period was selected. The glucose and lipid metabolism levels of the participants were measured by oral glucose tolerance test and insulin release test. Serum triglyceride levels were significantly higher in the obesity and non-obesity groups than in the control group (p<0.05). The serum triglyceride levels in the obesity and non-obesity groups were significantly higher than those in the control group (p<0.05) and the obesity group had the highest triglyceride content. The glucose metabolism level in the non-obesity group was significantly higher than that in the control group (p<0.05). The Homeostatic model assessment-beta in the control group was significantly higher than that in the obesity group and the non-obesity group, the obesity group had the lowest Homeostatic model assessment-insulin resistance; the Homeostatic model assessment-insulin resistance in the control group was significantly lower than that in the other two groups and the obesity group had the lowest Homeostatic model assessment-insulin resistance (p<0.05). Serum triglyceride levels in patients with polycystic ovary syndrome can reflect changes in glucose and lipid metabolism and triglyceride as an inexpensive and routine test can be considered as a surrogate indicator of insulin resistance in non-obesity patients with polycystic ovary syndrome.

Full-Text | PDF

 
 
List of Supporting Conferences