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Bioactive Compounds and Antimicrobial Activity of Glasswort Salicornia europaea

Author(s): S. Karan*, C. Turan, M. K.Sangun and E. A. E. Eliuz
Iskenderun Technical University, Faculty of Marine Science and Technology, Hatay 31200, 1Hatay Mustafa Kemal University, Faculty of Arts and Sciences, Department of Chemistry, Hatay 31060, 2Department of Food Technology, Vocational School of Technical Sciences, Mersin University, Mersin 33110, Turkey

Correspondence Address:
S. KARAN, Iskenderun Technical University, Faculty of Marine Science and Technology, Hatay 31200, Turkey, E-mail:

This study aims to determine the chemical and physical composition and antibacterial activity of glasswort. Soxhlet extraction of S. europaea was performed using Hexane and analyzed by Gas chromatographymass spectrometry. Alpha-tocopherol content was analysed by using Liquid chromatography with tandem mass spectrometry. The elemental analysis was investigated by inductively coupled plasma mass spectrometry. The crystallographic texture and composition of powder samples were determined by X-ray diffraction. The Minimum Inhibition Concentrations and inhibition zones extracts of S. europaea were performed by spectrophotometric broth microdilution and disc diffusion methods, respectively, against 4 bacteria (Escherichia coli, Klebsiella pneumonia, Bacillus subtilis, Staphylococcus aureus) and 2 fungi (Candida albicans, C. parapsilosis). Alpha-tocopherol quantity and oil content of S. europaea were found to be 2.1±0.3mg/100 g and 15.15 %, respectively. The detected minerals were also found as Na 447, Mg 51.98, K 45.86, Ca 14.27 ppm. The highest minimum inhibition concentration was 0.9 mg/mL against E. coli in methanol extract (p<0.05). The highest mean inhibition zones diameter was 3.8 mm for methanol extracts against B. subtilis (p<0.05). As a result, the extract and oil of S. europaea can be used as potential bioactive and antimicrobial agents for pharmaceutical and cosmetics applications.

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