Abstract
Bioconversion Of Cephalosporin-G To 7-Amino Deacetoxy Cephalosporanic Acid
Author(s): P Deshmukh, J. G Shewale, Meena Tripathi, S. C Chaturvedi
Cephalosporin-G (Ceph-G) was converted to 7-amino deacetoxycephalosporanic acid (7-ADCA) using immobilized penicillin-G acylase (ImPGA). Effect of different variables on the rate of hydrolysis using a recirculated packed bed reactor (RPBR) was studied. A comparison between a RPBR and a stirred tank reactor (STR) was carried out. The RPBR was found to be superior to STR.
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