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Abstract

Biological screening of mannich base derived from sulphamethoxazole.

Author(s): N Khosla, S Joshi
School of Chemistry, DAVV, Indore -452 001,

Correspondence Address:
N Khosla School of Chemistry, DAVV, Indore -452 001

Mannich base of P-nitrobenzamide was prepared using secondary aminesulphonamide. The synthesised product was identified by spectral technique i.e. IR and UV. The Mannich base was subjected to antimicrobial screening against various organisms using filter paper disc technique. The sensitivity of bacteria to antibacterial agent was tested against various concentration in mgs. The study revealed that synthesised Mannich base of p-nitrobenzamide was showing significant activity on bacteria as obtained on statistical calculations.

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