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Abstract

Captopril Combined with Nitroglycerin Injection for Hypertensive Emergency: An Analysis of Efficacy, Complication Rate and Blood Pressure Control

Author(s): Yang Xing and Fei Liu*
Department of Emergency Medicine, 1Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110000, China

Correspondence Address:
Fei Liu, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110000, China, E-mail: 18940255022@163.com


This study focuses on the efficacy of captopril combined with nitroglycerin injection on complication rate and blood pressure control in hypertensive emergency patients. 115 hypertensive emergency patients admitted between December, 2018 and December, 2022 were selected and divided into two groups in which 59 patients received captopril combined with nitroglycerin injection (research group) and 56 patients received nitroglycerin injection (control group). The curative effect, complication rate (vomiting, cough, increased heart rate, tinnitus, dizziness and pulsatile headache), blood pressure control (systolic and diastolic blood pressure), glucolipid metabolism (total cholesterol, triglyceride and fasting plasma glucose) and neurological function (based on National Institutes of Health Stroke Scale scores) were analyzed and compared. Evidently higher overall response and fewer complications were determined in the research group compared with the control group. The research group also showed notably lower post-treatment systolic, diastolic blood pressure, total cholesterol, triglyceride, fasting plasma glucose and National Institutes of Health Stroke Scale score than the control group. The above result shows that captopril combined with nitroglycerin injection can enhance efficacy in hypertensive emergency patients and is more conducive to blood pressure control with better clinical safety and efficacy.

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Citations : 61564

Indian Journal of Pharmaceutical Sciences received 61564 citations as per google scholar report