Abstract
Chemical Compositions and Anticancer Potential of`Essential Oil from Greenhouse-cultivated Ocimum basilicum Leaves
School of Pharmacy, 1Faculty of Science, Al Al-Bayt University, Mafraq, 2Hamdi Mango Center for Scientific Research, 3Cell Therapy Center, The University of Jordan, Amman-Jordan, 4Faculty of Pharmacy, Jordan University of Science and Technology, Irbid-Jordan
Correspondence Address:
School of Pharmacy, 1Faculty of Science, Al Al-Bayt University, Mafraq, 2Hamdi Mango Center for Scientific Research, Irbid-Jordan, E-mail: aburjai@ju.edu.jo
In the current study, the compositions of the essential oil obtained from leaves of Ocimum basilicum ‘Cinnamon’ grown in Jordan in a greenhouse was analysed. The antitumor activity of the essential oil was examined against three different cancer cell lines including MDA-MB-231, MCF7 and U-87 MG. The hydrodistillation method was used to extract the essential oil from Ocimum basilicum and the chemical components were analyzed and identified using gas chromatography-mass spectroscopy. The dry weight yield of essential oil was 0.50 % (w/w). Thirty-one components representing 97.80 % of the essential oil were identified. The main chemical components revealed the presence of linalool, eugenol, eucalyptol, hinesol, trans-α-bergamotene and γ-cadinene as the major constituents. In conclusion, the essential oil extracted from greenhouse cultivated Ocimum basilicum European chemotype showed potent antitumor activity.
